Nature

  • ‘Bandit’ algorithms help chemists to discover generally applicable conditions for reactions

    RESEARCH BRIEFINGS 18 March 2024 In organic chemistry, finding conditions that enable a broad range of compounds to undergo a particular type of reaction is highly desirable. However, conventional methods for doing so consume a lot of time and reagents. A machine-learning method has been developed that overcomes these problems. Source link

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  • an early-career researcher’s checklist for prioritizing projects

    Deciding which projects to pursue can be daunting, but a simple framework can help you to decide which ones are the best fit.Credit: Biwa Studio/Getty All three of us have, at some point in our academic careers, taken on one too many projects. For example, M. P. is finishing his PhD programme in management at the Wharton School of the…

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  • Divas, captains, ghosts, ants and bumble-bees: collaborator attitudes explained

    It takes all sorts: different collaborators approach projects in different ways, and managing relationships between them is a crucial challenge.Credit: Andriy Onufriyenko/Getty As a psychologist, I’m equipped with a theoretical understanding of emotions, attitudes, beliefs and behaviour – and, because of this, I might reasonably be expected to manage relationships with collaborators effectively. Some of my best memories of collaboration…

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  • what I learnt from using a time-tracking spreadsheet

    By monitoring where she spent her time, Megan Rogers could improve her working hours and track her achievements.Credit: Getty Starting a tenure-track faculty position can be daunting, with several seemingly equally important responsibilities competing for time. These include establishing a laboratory, launching research studies, writing grant applications, publishing papers and preparing and teaching courses. You also have to mentor students,…

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  • Inside China’s giant underground neutrino lab

    Kaiping, China Seven hundred metres below the rolling green landscape of Kaiping, southeast China, construction workers are furiously finishing a 35-metre-diameter orb-shaped detector that aims to observe ghostly subatomic particles known as neutrinos in exquisite detail. If all goes to plan, the US$376 million Jiangmen Underground Neutrino Observatory (JUNO) will be ready to start detecting by the end of this…

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  • APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia

    Single-nucleus RNA sequencing of human brain tissue Frozen superior frontal gyrus and fusiform gyrus tissue blocks and pathology clinical reports were obtained from the Banner Sun Health Research Institute Brain and Body Donation Program in accordance with institutional review boards and policies at both Stanford School of Medicine and Banner Sun Health Research Institute. All samples obtained from Banner Sun…

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  • China–US climate collaboration concerns as Xie and Kerry step down

    John Kerry and Xie Zhenhua’s friendship kept US–China climate negotiations rolling even when the two countries disagreed on other matters.Credit: Fadel Dawod/Getty Researchers are regarding the parallel departures of the US and Chinese climate envoys with apprehension, saying that the change could rattle the current co-operative spirit between the world’s two biggest carbon emitters. John Kerry’s term as US climate…

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  • Biden seeks to boost science funding — but his budget faces an ominous future

    President Biden visits the US National Institutes of Health, which under his proposed budget would receive roughly the same amount of funding in the 2025 fiscal year as in the 2023 fiscal year.Credit: Chris Kleponis/CNP/Bloomberg via Getty US President Joe Biden today proposed modest increases in federal spending on science and innovation for the 2025 fiscal year. But that doesn’t…

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  • Roger Guillemin (1924–2024), neuroscientist who showed how the brain controls hormones

    Credit: Hulton Archive/Getty Roger Guillemin identified the molecules in the brain that control the production of hormones in endocrine glands such as the pituitary and thyroid. His work led to a torrent of advances in neuroendocrinology, with far-reaching effects on studies of metabolism, reproduction and growth. For his discoveries on peptide-hormone production in the brain, Guillemin shared the 1977 Nobel…

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  • the inside story of deception in a rising star’s physics lab

    In 2020, Ranga Dias was an up-and-coming star of the physics world. A researcher at the University of Rochester in New York, Dias achieved widespread recognition for his claim to have discovered the first room-temperature superconductor, a material that conducts electricity without resistance at ambient temperatures. Dias published that finding in a landmark Nature paper1. Nearly two years later, that…

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